At iWinDirect, we aim to cut through the hype. Why pay for expensive products that are designed to maximize profit rather than maximize your results? And besides, who do you think pays for all of those fancy ads? That’s right: The consumer.
So we’ll start cutting through the hype, first with a look at Creatine Monohydrate. Few would deny that creatine is one of the most effective performance-enhancing supplements that you can buy, so why muddle everything with a bunch of add-ons that are either scientifically questionable or ineffective at the low levels many companies decide to toss in there?
What is Creatine Monohydrate?
Creatine is a nutrient found naturally in the human body, where it is crucial to muscular contraction. It is formed in the liver by a metabolic pathway that requires the amino acids glycine, arginine, and methionine. It can also be obtained from foods such as red meat, fish, and chicken. In the human body, almost all creatine is found in muscle cells.
When taken as an oral supplement, creatine increases the amount of energy available to working muscles, meaning that muscles can work harder and longer. If you’re a recreational or competitive athlete, or if you use your muscles at work, then you can benefit from creatine supplementation.
To understand how creatine functions as a performance-enhancing supplement, it is necessary to have a basic understanding of the energetics of muscle contraction. Each individual muscle fibre contains two types of filaments: thick filaments and thin filaments. The contraction of muscle is due to the shortening of individual muscle fibres as these filaments slide together. Energy is required to slide the filaments together and cause muscle contraction, and this energy must come in the form of ATP (adenosine triphosphate). ATP is the ‘energy currency’ of the muscle cell. Its unique chemical structure allows it to store a great deal of energy, and to transfer this energy to other molecules, which provides the energy that drives many metabolic processes of the body. Muscle contraction occurs as ATP provides the energy needed to pull together the filaments of the contracting muscle. The energy stored in ATP is transferred to myosin, resulting in energized myosin and ADP (Adenosine Diphosphate), as outlined below.
ATP + muscle ==> ADP + energized muscle
The energizing of muscle must occur many times, using up a number of ATP molecules, in order to fully contract a muscle. The pool of available ATP in the muscle cell is very rapidly depleted, however, and new ATP must be produced for muscular contraction to continue (the ATP pool contains only enough energy for about 1-2 seconds). A deficit of ATP in contracting muscle results in fatigue and decreased strength, power, and endurance. The fastest way in which ATP is regenerated in the muscle cell is through the high-energy molecule creatine phosphate (CrP). This molecule, which comprises about two thirds of the creatine found in muscle cells, rapidly regenerates ATP from ADP, as outlined below. The ATP produced is then available to fuel further muscle contraction.
Creatine phosphate + ADP ==> Creatine + ATP
Published reports estimate that the pool of creatine phosphate will be depleted within approximately 10 seconds during high intensity muscular contraction. Increasing the amount of available creatine phosphate increases the rate at which ATP is made available to contracting muscle cells.
Oral supplementation with Creatine Monohydrate has been proven in scientific trials and studies to increase the amount of creatine and phosphocreatine in muscle cells. This increase in PCr allows the muscles to work harder and longer, making Creatine Monohydrate an effective ergogenic supplement.
If you have any doubt about the science behind the use of creatine monohydrate, note that the extremely strict Canadian Natural Health Products Directorate has even reviewed the research and concluded that the following claims can be made on this amazing compound:
• Increases fat-free/body/muscle/lean mass/size when used in conjunction with a resistance training regimen
• Improves strength/power/performance in repetitive bouts of brief, highly-intense physical activity (e.g. sprints, jumping, resistance training)
Let’s see the latest “scientifically engineered” or “concentrated” creatine try that.
Visit www.iwindirect.com for your creatine requirements. Available in powder and capsule form.
- Balsom, et al., 1994. Creatine in Humans with Special Reference to Creatine Supplementation. Sports Med 18:268-280.
- Balsom, et al., 1995. Skeletal muscle metabolism during short duration high-intensity exercise: influence of creatine supplementation. Acta Physiol Scand 154:303-310.
- Bemben MG, Bemben DA, Loftiss DD, Knehans AW. 2001. Creatine supplementation during resistance training in college football athletes. Medicine & Science in Sports & Exercise 33(10):1667-1673.
- Brannon, et al., 1997. Effects of creatine loading and training on running performance and biochemical properties of rat skeletal muscle. Med Sci Sports Exerc 29:489-495.
- Brose A, Parise G, Tarnopolsky MA. 2003. Creatine supplementation enhances isometric strength and body composition improvements following strength exercise training in older adults. The Journals of Gerontology Series A: Biological Science and Medical Science 58(1):11-19.
- Casey, et al., 1996. Creatine ingestion favorably affects performance and muscle metabolism during maximal exercise in humans. Am J Physiol 271:E31-E37.
- Clark, 1998. Creatine: a review of its nutritional applications in sport. Nutrition 14:322-324.
- Dash AK, Sawhney A. 2002. A simple LC method with UV detection for the analysis of creatine and creatinine and its application to several creatine formulations. Journal of Pharmaceutical and Biomedical Analysis 29(5):939-945.
- Earnest, et al., 1995. The effect of creatine monohydrate ingestion on anaerobic power indices, muscular strength and body composition. Acta Physiol Scand 153:207-209.
- Earnest, et al., 1997. Effects of Creatine Monohydrate Ingestion on Intermediate Duration Anaerobic Treadmill Running to Exhaustion. J Strength and Cond Res 11:234-238.
- Ekblom, 1996. Effects of Creatine Supplementation on Performance. Am J Sports Med 24:S38-S39.
- Engelhardt, et al., 1998. Creatine supplementation in endurance sports. Med Sci Sports Exerc 30:1123-1129.
- Feldman, 1999. Creatine: A dietary supplement and ergogenic aid. Nutr Rev 57:45-50.
- Green, et al., 1996. Carbohydrate ingestion augments skeletal muscle creatine accumulation during creatine supplementation in humans. Am J Physiol 271:E821-E826.
- Greenhaff, et al., 1993. The influence of oral creatine supplementation on muscle phosphocreatine synthesis following intense contraction in man. J Physiol 467:75P.
- Greenhaff, et al., 1994. Effect of oral creatine supplementation on skeletal muscle phosphocreatine resynthesis. Am J Physiol 266:E725-E730.
- Hespel P, Eijnde BO, van Leemputte M. 2002. Opposite actions of caffeine and creatine on muscle relaxation time in humans. Journal of Applied Physiology 92(2):513-518.
- Kelly and Jenkins, 1998. Effect of Oral Creatine Supplementation on Near-Maximal Strength and Repeated Sets of High-Intensity Bench Press Exercise. J Strength and Cond Res 12:109-115.
- Mathews and van Holde, 1991. Biochemistry. The Benjamin/Cummings Publishing Company, Inc. New York.
- Maughan, 1995. Creatine Supplementation and Exercise Performance. Int J Sports Nutr 5:94-101.
- Noonan, et al., 1998. Effects of Varying Dosages of Oral Creatine Relative to Fat Free Body Mass on Strength and Body Composition. J Strength and Cond Res 12:104-108.
- Okudan N, Gökbel H. 2005. The effects of creatine supplementation on performance during the repeated bouts of supramaximal exercise. Journal of Sports Medicine and Physical Fitness 45(4):507-512.
- Steenge, et al., 1998. Stimulatory effect of insulin on creatine accumulation in human skeletal muscle. Am J Physiol 275:E974-E979.
- Vandenberghe, et al., 1997. Long-term creatine intake is beneficial to muscle performance during resistance training. J Appl Physiol 83:2055-2063.
- Van Leemputte, et al., 1999. Shortening of muscle relaxation time after creatine loading. J Appl Physiol 86:840-844.
- Volek, et al., 1997. Creatine supplementation enhances muscular performance during high-intensity resistance exercise. J Am Diet Assoc 97:765-770.